After her studies of literature and art history at the École Normale Supérieure in her hometown Paris, Mariame Clément lived in the U.S.A. and in Berlin, where she began a PhD on medieval Persian miniature painting.
After an internship at the Staatsoper Unter den Linden, she started working as an assistant director for various opera houses in Europe.
In 2003, she won the third prize at the European Competition for opera directors in Wiesbaden.
She made her directing debut in 2004 with Rossini's Il Signor Bruschino and Puccini's Gianni Schicchi in Lausanne. Her second production, Rossini's Il Viaggio a Reims in Bern, was revived in Oviedo, Tel-Aviv and Antwerp.
Since then, she has worked Athens (Le Comte Ory), Bern (La Traviata, Il Barbiere di Siviglia, La Bohème), Strasbourg (La Belle Hélène, Werther, Platée, Der Rosenkavalier, Die Zauberflöte, Das Liebesverbot), Antwerp/Ghent (Giasone, Agrippina, Rossini's Armida), at the Theater an der Wien (Castor et Pollux, The Fairy Queen), in Graz (Faust, Die Zauberflöte), in Dortmund (Le Nozze di Figaro), in Nuremberg (Platée, Le Nozze di Figaro), in Glyndebourne (Don Pasquale, Poliuto), at the Opéra national de Paris (Hänsel und Gretel), in Essen (Le Grand Macabre), and at the Royal Opera House (L'Étoile).
In 2014 she staged a world premiere by Philippe Hurel, Les Pigeons d'argile, at the Théâtre du Capitole in Toulouse.
Further projects will take her to Paris (Théâtre des Champs-Élysées), Essen, Dresden, Santiago...